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pentobarbital will minimize the level or outcome of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.Barbiturates can induce hepatic microsomal enzymes causing enhanced metabolism and diminished anticoagulant reaction of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); people stabilized on anticoag